Contamination control and aseptic processing are at the heart of producing safe, effective, and sterile pharmaceutical products—especially in sterile manufacturing. With the latest updates to EU Annex 1 and guidance like PDA Technical Report 90, there’s a clear shift toward a more holistic, science- and risk-based approach. Rather than relying on isolated controls, the expectation now is to build an integrated Contamination Control Strategy (CCS) that connects facility design